human umbilical artery endothelial cells (Cell Applications Inc)
Structured Review

Human Umbilical Artery Endothelial Cells, supplied by Cell Applications Inc, used in various techniques. Bioz Stars score: 94/100, based on 34 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/huaecs/Human+Umbilical+Artery+Endothelial+Cells%3A+HUAEC/pmc12751044-103-0-8
Average 94 stars, based on 34 article reviews
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1) Product Images from "Caspase-1 inhibition mitigates neonatal hyperoxia-induced vascular and cardiopulmonary inflammation in neonatal rats"
Article Title: Caspase-1 inhibition mitigates neonatal hyperoxia-induced vascular and cardiopulmonary inflammation in neonatal rats
Journal: Clinical Science (London, England : 1979)
doi: 10.1042/CS20242275
Figure Legend Snippet: Treatment with caspase-1 inhibitor decreased gene expression of ( A ) IL-1β, ( B ) GSDMD and protein expression of ( C ) IL-1β, ( D ) GSDMD in hyperoxia-exposed endothelial cells. ( E ) Representative western blots of IL-1β and of GSDMD in the endothelial cells. In addition, caspase-1 inhibitor also reduced gene expression of ( F ) IL-1β ( G ) GSDMD and protein expression of ( H ) IL-1β, ( I ) GSDMD in hyperoxia-exposed smooth muscle cells. ( J ) Representative western blots of IL-1β and of GSDMD in the smooth muscle cells. n = 4–5/group, data are mean ± SD, two-way ANOVA with Tukey’s multiple comparisons test. * P <0.05 ** P <0.01, *** P <0.001; **** P <0.0001. HYP, hyperoxia; PL, placebo; RA, room air; VX-765, caspase-1 Inhibitor.
Techniques Used: Gene Expression, Expressing, Western Blot
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